Expression, purification and preliminary crystallographic analysis of Pseudomonas aeruginosa RocR protein

Masayo Kotaka*, Sujit Dutta, Hooi Chen Lee, Mitchell J.M. Lim, Yeehwa Wong, Feng Rao, Edward P. Mitchell, Zhao Xun Liang, Julien Lescar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Pseudomonas aeruginosa RocR, an EAL-domain protein which regulates the expression of virulence genes and biofilm formation, has been cloned and expressed in Escherichia coli and purified. Here, the crystallization and preliminary diffraction analysis of RocR are reported. The X-ray diffraction data were processed to a resolution of 2.50 Å. The crystals belonged to space group P6122 or P6522, with unit-cell parameters a = 118.8, b = 118.8, c = 495.1 Å, = Β = 90, = 120°.

Original languageEnglish
Pages (from-to)1035-1038
Number of pages4
JournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
Volume65
Issue number10
DOIs
Publication statusPublished - 2009
Externally publishedYes

ASJC Scopus Subject Areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Genetics
  • Condensed Matter Physics

Keywords

  • EAL-domain proteins
  • Pseudomonas aeruginosa
  • RocR

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