Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions

Shun Jun Ji; Shun Yi Wang; Yong Zhang; Teck Peng Loh

doi:10.1016/j.tet.2003.12.060

Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions

Shun Jun Ji^*, Shun Yi Wang, Yong Zhang, Teck Peng Loh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

289 Citations (Scopus)

Abstract

Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of I₂ under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.

Original language	English
Pages (from-to)	2051-2055
Number of pages	5
Journal	Tetrahedron
Volume	60
Issue number	9
DOIs	https://doi.org/10.1016/j.tet.2003.12.060
Publication status	Published - Feb 23 2004
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Aldehydes
Bis(indolyl)methanes
Indoles
Iodine
Solvent-free

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10.1016/j.tet.2003.12.060

Cite this

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title = "Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions",

abstract = "Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of I2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.",

keywords = "Aldehydes, Bis(indolyl)methanes, Indoles, Iodine, Solvent-free",

author = "Ji, \{Shun Jun\} and Wang, \{Shun Yi\} and Yong Zhang and Loh, \{Teck Peng\}",

year = "2004",

month = feb,

day = "23",

doi = "10.1016/j.tet.2003.12.060",

language = "English",

volume = "60",

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journal = "Tetrahedron",

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publisher = "Elsevier Limited",

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TY - JOUR

T1 - Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions

AU - Ji, Shun Jun

AU - Wang, Shun Yi

AU - Zhang, Yong

AU - Loh, Teck Peng

PY - 2004/2/23

Y1 - 2004/2/23

N2 - Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of I2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.

AB - Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of I2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.

KW - Aldehydes

KW - Bis(indolyl)methanes

KW - Indoles

KW - Iodine

KW - Solvent-free

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U2 - 10.1016/j.tet.2003.12.060

DO - 10.1016/j.tet.2003.12.060

M3 - Article

AN - SCOPUS:1042298780

SN - 0040-4020

VL - 60

SP - 2051

EP - 2055

JO - Tetrahedron

JF - Tetrahedron

IS - 9

ER -

Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions

Abstract

ASJC Scopus Subject Areas

Keywords

Access to Document

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