Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring

Yueyue Jiang, Fanben Meng, Dianpeng Qi, Pingqiang Cai, Zongyou Yin, Fangwei Shao, Hua Zhang, Freddy Boey, Xiaodong Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.

Original languageEnglish
Pages (from-to)2260-2265
Number of pages6
JournalSmall
Volume9
Issue number13
DOIs
Publication statusPublished - Jul 8 2013
Externally publishedYes

ASJC Scopus Subject Areas

  • Biotechnology
  • General Chemistry
  • Biomaterials
  • General Materials Science
  • Engineering (miscellaneous)

Keywords

  • adenosine triphosphate
  • nanotip arrays
  • raman scattering
  • redox electrochemistry

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