Highly enantioselective Cu(I)-Tol-BINAP-catalyzed asymmetric conjugate addition of Grignard reagents to α,β-unsaturated esters

Keyphrases

• 1,4-Conjugate Addition 40%
• Alkyl Esters 20%
• Asymmetric 1 20%
• Asymmetric Conjugate Addition 100%
• BINAP 100%
• C-C Bond 20%
• Catalytic System 20%
• Chiral Ligands 20%
• Conjugate Addition 20%
• Conjugate Addition Reaction 40%
• Copper-catalyzed 20%
• Cu(I) 100%
• Diastereoselectivity 20%
• Enantioselectivity 100%
• Geometrical Isomers 20%
• Good Yield 20%
• Grignard Reagents 100%
• High Enantioselectivity 20%
• Michael Acceptor 20%
• Organometallic Compounds 20%
• Organometallic Reagents 20%
• Regio 20%
• Regioselectivity 20%
• Unsaturated Esters 100%
• α,β-unsaturated Carbonyl Compounds 20%

Chemistry

• Addition Reaction 40%
• Carbonyl Compound 20%
• Chemistry 20%
• Cis Trans Isomer 20%
• Diastereoselectivity 20%
• Enantiomer 40%
• Enantioselectivity 40%
• Grignard Reagent 100%
• Metallocene 20%
• Michael Reaction 20%
• Organometallic Compound 20%
• Regioselectivity 20%