Highly stereoselective prins cyclization of (2)- And (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

Feng Liu; Teck Peng Loh

doi:10.1021/ol070506n

Highly stereoselective prins cyclization of (2)- And (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

Feng Liu, Teck Peng Loh^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

Abstract

An efficient method has been developed to construct 2,6-cis-4,5-dibromo- tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.

Original language	English
Pages (from-to)	2063-2066
Number of pages	4
Journal	Organic Letters
Volume	9
Issue number	11
DOIs	https://doi.org/10.1021/ol070506n
Publication status	Published - May 24 2007
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol070506n

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title = "Highly stereoselective prins cyclization of (2)- And (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans",

abstract = "An efficient method has been developed to construct 2,6-cis-4,5-dibromo- tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.",

author = "Feng Liu and Loh, \{Teck Peng\}",

year = "2007",

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day = "24",

doi = "10.1021/ol070506n",

language = "English",

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journal = "Organic Letters",

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T1 - Highly stereoselective prins cyclization of (2)- And (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

AU - Liu, Feng

AU - Loh, Teck Peng

PY - 2007/5/24

Y1 - 2007/5/24

N2 - An efficient method has been developed to construct 2,6-cis-4,5-dibromo- tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.

AB - An efficient method has been developed to construct 2,6-cis-4,5-dibromo- tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.

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JO - Organic Letters

JF - Organic Letters

IS - 11

ER -

Highly stereoselective prins cyclization of (2)- And (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

Abstract

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