How nanoparticles interact with cancer cells

Abdullah Syed; Warren C.W. Chan

doi:10.1007/978-3-319-16555-4_10

How nanoparticles interact with cancer cells

Abdullah Syed, Warren C.W. Chan^*

^*Corresponding author for this work

University of Toronto

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

There are currently no nanoparticle formulations that optimally target diseased cells in the body. A small percentage of nanoparticles reach these cells and most accumulate in cells of the mononuclear phagocytic system. This chapter explores the interactions between nanoparticles and cells that may explain the causes for off-target accumulation of nanoparticles. A greater understanding of the nanoparticle-cellular interactions will lead to improvements in particle design for improved therapeutic outcome.

Original language	English
Pages (from-to)	227-244
Number of pages	18
Journal	Cancer Treatment and Research
Volume	166
DOIs	https://doi.org/10.1007/978-3-319-16555-4_10
Publication status	Published - 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2015.

ASJC Scopus Subject Areas

Oncology
Cancer Research

Keywords

Cancer targeting
Nano-biointeractions
Nanomedicine
Nanoparticle cell interaction

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/978-3-319-16555-4_10

Cite this

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AB - There are currently no nanoparticle formulations that optimally target diseased cells in the body. A small percentage of nanoparticles reach these cells and most accumulate in cells of the mononuclear phagocytic system. This chapter explores the interactions between nanoparticles and cells that may explain the causes for off-target accumulation of nanoparticles. A greater understanding of the nanoparticle-cellular interactions will lead to improvements in particle design for improved therapeutic outcome.

KW - Cancer targeting

KW - Nano-biointeractions

KW - Nanomedicine

KW - Nanoparticle cell interaction

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ER -

How nanoparticles interact with cancer cells

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

UN SDGs

Access to Document

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Cite this