Hybrid Janus Microparticles Achieving Selective Encapsulation for Theranostic Applications via a Facile Solvent Emulsion Method

Yi Guang Jerome Lim; Kwok Choon Wilson Poh; Say Chye Joachim Loo

doi:10.1002/marc.201800801

Hybrid Janus Microparticles Achieving Selective Encapsulation for Theranostic Applications via a Facile Solvent Emulsion Method

Yi Guang Jerome Lim, Kwok Choon Wilson Poh, Say Chye Joachim Loo^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Anisotropic Janus particles composed of biocompatible polymers have been gaining considerable interest for biomedical applications. Here, the fabrication of hybrid Janus particles via a single-step solvent emulsion technique, potentially for theranostic purposes, is shown. Through this technique, the selective encapsulation of therapeutic and diagnostic agents is streamlined into different “faces” of the Janus structure. This facile technique is used to seamlessly fabricate polymeric-based hybrid Janus particles for theranostic applications with little complexity.

Original language	English
Article number	1800801
Journal	Macromolecular Rapid Communications
Volume	40
Issue number	7
DOIs	https://doi.org/10.1002/marc.201800801
Publication status	Published - Apr 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

ASJC Scopus Subject Areas

Organic Chemistry
Polymers and Plastics
Materials Chemistry

Keywords

biocompatible
biodegradable
co-encapsulation
controlled release
delivery systems
nanoparticles

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10.1002/marc.201800801

Cite this

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abstract = "Anisotropic Janus particles composed of biocompatible polymers have been gaining considerable interest for biomedical applications. Here, the fabrication of hybrid Janus particles via a single-step solvent emulsion technique, potentially for theranostic purposes, is shown. Through this technique, the selective encapsulation of therapeutic and diagnostic agents is streamlined into different “faces” of the Janus structure. This facile technique is used to seamlessly fabricate polymeric-based hybrid Janus particles for theranostic applications with little complexity.",

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AU - Loo, Say Chye Joachim

PY - 2019/4

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AB - Anisotropic Janus particles composed of biocompatible polymers have been gaining considerable interest for biomedical applications. Here, the fabrication of hybrid Janus particles via a single-step solvent emulsion technique, potentially for theranostic purposes, is shown. Through this technique, the selective encapsulation of therapeutic and diagnostic agents is streamlined into different “faces” of the Janus structure. This facile technique is used to seamlessly fabricate polymeric-based hybrid Janus particles for theranostic applications with little complexity.

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KW - delivery systems

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Hybrid Janus Microparticles Achieving Selective Encapsulation for Theranostic Applications via a Facile Solvent Emulsion Method

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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