Hydrazone derivatives in agrochemical discovery and development

Ya Wang; Shengxin Guo; Lijiao Yu; Wei Zhang; Zhenchao Wang; Yonggui Robin Chi; Jian Wu

doi:10.1016/j.cclet.2023.108207

Hydrazone derivatives in agrochemical discovery and development

Ya Wang, Shengxin Guo, Lijiao Yu, Wei Zhang, Zhenchao Wang^*, Yonggui Robin Chi, Jian Wu

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

25 Citations (Scopus)

Abstract

As a common active substructure, hydrazone has attracted increasing attention and is considered essential for pesticide discovery. It has been widely regarded as a potential insecticidal, antibacterial, antifungal, antiviral, and herbicidal agent. In this review, we highlight the pesticide versatility of hydrazone fragments and provide a comprehensive summary of the biological activity, structure-activity relationship analysis (SARs), and primary mechanism of their analogs. This profile is expected to give valuable information for discovering new pesticides.

Original language	English
Article number	108207
Journal	Chinese Chemical Letters
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/j.cclet.2023.108207
Publication status	Published - Mar 2024
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2023

ASJC Scopus Subject Areas

General Chemistry

Keywords

Agrochemicals
Biological activity
Hydrazone
Preliminary mechanism
Structure-activity relationship

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10.1016/j.cclet.2023.108207

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title = "Hydrazone derivatives in agrochemical discovery and development",

abstract = "As a common active substructure, hydrazone has attracted increasing attention and is considered essential for pesticide discovery. It has been widely regarded as a potential insecticidal, antibacterial, antifungal, antiviral, and herbicidal agent. In this review, we highlight the pesticide versatility of hydrazone fragments and provide a comprehensive summary of the biological activity, structure-activity relationship analysis (SARs), and primary mechanism of their analogs. This profile is expected to give valuable information for discovering new pesticides.",

keywords = "Agrochemicals, Biological activity, Hydrazone, Preliminary mechanism, Structure-activity relationship",

author = "Ya Wang and Shengxin Guo and Lijiao Yu and Wei Zhang and Zhenchao Wang and Chi, {Yonggui Robin} and Jian Wu",

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doi = "10.1016/j.cclet.2023.108207",

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T1 - Hydrazone derivatives in agrochemical discovery and development

AU - Wang, Ya

AU - Guo, Shengxin

AU - Yu, Lijiao

AU - Zhang, Wei

AU - Wang, Zhenchao

AU - Chi, Yonggui Robin

AU - Wu, Jian

PY - 2024/3

Y1 - 2024/3

N2 - As a common active substructure, hydrazone has attracted increasing attention and is considered essential for pesticide discovery. It has been widely regarded as a potential insecticidal, antibacterial, antifungal, antiviral, and herbicidal agent. In this review, we highlight the pesticide versatility of hydrazone fragments and provide a comprehensive summary of the biological activity, structure-activity relationship analysis (SARs), and primary mechanism of their analogs. This profile is expected to give valuable information for discovering new pesticides.

AB - As a common active substructure, hydrazone has attracted increasing attention and is considered essential for pesticide discovery. It has been widely regarded as a potential insecticidal, antibacterial, antifungal, antiviral, and herbicidal agent. In this review, we highlight the pesticide versatility of hydrazone fragments and provide a comprehensive summary of the biological activity, structure-activity relationship analysis (SARs), and primary mechanism of their analogs. This profile is expected to give valuable information for discovering new pesticides.

KW - Agrochemicals

KW - Biological activity

KW - Hydrazone

KW - Preliminary mechanism

KW - Structure-activity relationship

UR - http://www.scopus.com/inward/record.url?scp=85181147917&partnerID=8YFLogxK

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DO - 10.1016/j.cclet.2023.108207

M3 - Review article

AN - SCOPUS:85181147917

SN - 1001-8417

VL - 35

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 3

M1 - 108207

ER -

Hydrazone derivatives in agrochemical discovery and development

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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