Hydroxyapatite bioceramics reinforced with silica-coated graphene

Li Zhong; Bi Shuguang; Li Ruitao; Khor Khiam Aik

doi:10.4028/www.scientific.net/KEM.758.150

Hydroxyapatite bioceramics reinforced with silica-coated graphene

Li Zhong, Bi Shuguang, Li Ruitao, Khor Khiam Aik^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

Challenges facing graphene-reinforced composites include insufficient interfacial strengths, filler agglomeration, and their potential cytotoxicity. To tackle these challenges, silica-coated graphene (S-G) is used to toughen a representative bioceramic, hydroxyapatite (HA), and HA-based composites were prepared by spark plasma sintering. By adding 2 wt.% silica-coated graphene oxide, a precursor to S-G, the fracture toughness of HA could be increased by 84%. Compared with graphene/HA pellets, the S-G/HA samples showed superior mechanical properties. In addition, the incorporation of S-G could promote the proliferation and differentiation of human osteoblast-like cells MG63, and showed no adverse effect on their viability. Therefore, the bioceramic-based materials presented here possess great potential in load-bearing orthopedic implants.

Original language	English
Title of host publication	Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine
Editors	Christian Rey, Christele Combes, Christophe Drouet
Publisher	Trans Tech Publications Ltd
Pages	150-154
Number of pages	5
ISBN (Print)	9783035712209
DOIs	https://doi.org/10.4028/www.scientific.net/KEM.758.150
Publication status	Published - 2017
Externally published	Yes
Event	29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017 - Toulouse, France Duration: Oct 25 2017 → Oct 27 2017

Publication series

Name	Key Engineering Materials
Volume	758 KEM
ISSN (Print)	1013-9826
ISSN (Electronic)	1662-9795

Conference

Conference	29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017
Country/Territory	France
City	Toulouse
Period	10/25/17 → 10/27/17

Bibliographical note

Publisher Copyright:
© 2017 Trans Tech Publications, Switzerland.

ASJC Scopus Subject Areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

Keywords

Biocompatibility
Fracture toughness
Graphene oxide
Hydroxyapatite
Silica
Spark plasma sintering

Access to Document

10.4028/www.scientific.net/KEM.758.150

Cite this

Zhong, L., Shuguang, B., Ruitao, L., & Aik, K. K. (2017). Hydroxyapatite bioceramics reinforced with silica-coated graphene. In C. Rey, C. Combes, & C. Drouet (Eds.), Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine (pp. 150-154). (Key Engineering Materials; Vol. 758 KEM). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.758.150

@inproceedings{c2e3950c36ea4c1a842ac2f19aca92e9,

title = "Hydroxyapatite bioceramics reinforced with silica-coated graphene",

abstract = "Challenges facing graphene-reinforced composites include insufficient interfacial strengths, filler agglomeration, and their potential cytotoxicity. To tackle these challenges, silica-coated graphene (S-G) is used to toughen a representative bioceramic, hydroxyapatite (HA), and HA-based composites were prepared by spark plasma sintering. By adding 2 wt.% silica-coated graphene oxide, a precursor to S-G, the fracture toughness of HA could be increased by 84%. Compared with graphene/HA pellets, the S-G/HA samples showed superior mechanical properties. In addition, the incorporation of S-G could promote the proliferation and differentiation of human osteoblast-like cells MG63, and showed no adverse effect on their viability. Therefore, the bioceramic-based materials presented here possess great potential in load-bearing orthopedic implants.",

keywords = "Biocompatibility, Fracture toughness, Graphene oxide, Hydroxyapatite, Silica, Spark plasma sintering",

author = "Li Zhong and Bi Shuguang and Li Ruitao and Aik, {Khor Khiam}",

note = "Publisher Copyright: {\textcopyright} 2017 Trans Tech Publications, Switzerland.; 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017 ; Conference date: 25-10-2017 Through 27-10-2017",

year = "2017",

doi = "10.4028/www.scientific.net/KEM.758.150",

language = "English",

isbn = "9783035712209",

series = "Key Engineering Materials",

publisher = "Trans Tech Publications Ltd",

pages = "150--154",

editor = "Christian Rey and Christele Combes and Christophe Drouet",

booktitle = "Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine",

}

Zhong, L, Shuguang, B, Ruitao, L & Aik, KK 2017, Hydroxyapatite bioceramics reinforced with silica-coated graphene. in C Rey, C Combes & C Drouet (eds), Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine. Key Engineering Materials, vol. 758 KEM, Trans Tech Publications Ltd, pp. 150-154, 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017, Toulouse, France, 10/25/17. https://doi.org/10.4028/www.scientific.net/KEM.758.150

Hydroxyapatite bioceramics reinforced with silica-coated graphene. / Zhong, Li; Shuguang, Bi; Ruitao, Li et al.
Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine. ed. / Christian Rey; Christele Combes; Christophe Drouet. Trans Tech Publications Ltd, 2017. p. 150-154 (Key Engineering Materials; Vol. 758 KEM).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Hydroxyapatite bioceramics reinforced with silica-coated graphene

AU - Zhong, Li

AU - Shuguang, Bi

AU - Ruitao, Li

AU - Aik, Khor Khiam

PY - 2017

Y1 - 2017

N2 - Challenges facing graphene-reinforced composites include insufficient interfacial strengths, filler agglomeration, and their potential cytotoxicity. To tackle these challenges, silica-coated graphene (S-G) is used to toughen a representative bioceramic, hydroxyapatite (HA), and HA-based composites were prepared by spark plasma sintering. By adding 2 wt.% silica-coated graphene oxide, a precursor to S-G, the fracture toughness of HA could be increased by 84%. Compared with graphene/HA pellets, the S-G/HA samples showed superior mechanical properties. In addition, the incorporation of S-G could promote the proliferation and differentiation of human osteoblast-like cells MG63, and showed no adverse effect on their viability. Therefore, the bioceramic-based materials presented here possess great potential in load-bearing orthopedic implants.

AB - Challenges facing graphene-reinforced composites include insufficient interfacial strengths, filler agglomeration, and their potential cytotoxicity. To tackle these challenges, silica-coated graphene (S-G) is used to toughen a representative bioceramic, hydroxyapatite (HA), and HA-based composites were prepared by spark plasma sintering. By adding 2 wt.% silica-coated graphene oxide, a precursor to S-G, the fracture toughness of HA could be increased by 84%. Compared with graphene/HA pellets, the S-G/HA samples showed superior mechanical properties. In addition, the incorporation of S-G could promote the proliferation and differentiation of human osteoblast-like cells MG63, and showed no adverse effect on their viability. Therefore, the bioceramic-based materials presented here possess great potential in load-bearing orthopedic implants.

KW - Biocompatibility

KW - Fracture toughness

KW - Graphene oxide

KW - Hydroxyapatite

KW - Silica

KW - Spark plasma sintering

UR - http://www.scopus.com/inward/record.url?scp=85035042215&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85035042215&partnerID=8YFLogxK

U2 - 10.4028/www.scientific.net/KEM.758.150

DO - 10.4028/www.scientific.net/KEM.758.150

M3 - Conference contribution

AN - SCOPUS:85035042215

SN - 9783035712209

T3 - Key Engineering Materials

SP - 150

EP - 154

BT - Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine

A2 - Rey, Christian

A2 - Combes, Christele

A2 - Drouet, Christophe

PB - Trans Tech Publications Ltd

T2 - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017

Y2 - 25 October 2017 through 27 October 2017

ER -

Hydroxyapatite bioceramics reinforced with silica-coated graphene

Abstract

Publication series

Conference

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

Other files and links

Fingerprint

Cite this