In vivo bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities

René M. Werkmeister; Nikolaus Dragostinoff; Michael Pircher; Erich Götzingera; Christoph K. Hitzenberger; Rainer A. Leitgeb; Leopold Schmetterer

doi:10.1117/12.809382

In vivo bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities

René M. Werkmeister, Nikolaus Dragostinoff, Michael Pircher, Erich Götzingera, Christoph K. Hitzenberger, Rainer A. Leitgeb, Leopold Schmetterer

Medical University of Vienna

Research output: Contribution to journal › Conference article › peer-review

Abstract

A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.

Original language	English
Article number	71681P
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7168
DOIs	https://doi.org/10.1117/12.809382
Publication status	Published - 2009
Externally published	Yes
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII - San Jose, CA, United States Duration: Jan 26 2009 → Jan 28 2009

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Keywords

Absolute velocity
Bidirectional
Blood flow
Doppler OCT

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10.1117/12.809382

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Werkmeister, R. M., Dragostinoff, N., Pircher, M., Götzingera, E., Hitzenberger, C. K., Leitgeb, R. A., & Schmetterer, L. (2009). In vivo bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 7168, Article 71681P. https://doi.org/10.1117/12.809382

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abstract = "A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.",

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AU - Werkmeister, René M.

AU - Dragostinoff, Nikolaus

AU - Pircher, Michael

AU - Götzingera, Erich

AU - Hitzenberger, Christoph K.

AU - Leitgeb, Rainer A.

AU - Schmetterer, Leopold

PY - 2009

Y1 - 2009

N2 - A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.

AB - A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.

KW - Absolute velocity

KW - Bidirectional

KW - Blood flow

KW - Doppler OCT

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ER -

In vivo bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities

Abstract

ASJC Scopus Subject Areas

Keywords

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