Indium-mediated propargylation of aldehydes: Regioselectivity and enantioselectivity studies

Teck Peng Loh*, Man Jing Lin, Kee Leng Tan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)

Abstract

An enantioselective propargylation reaction of aldehydes with enantioselectivity up to 85% has been achieved in organic solvents by using stoichiometric amounts of (-)-cinchonidine as the chiral source.

Original languageEnglish
Pages (from-to)507-509
Number of pages3
JournalTetrahedron Letters
Volume44
Issue number3
DOIs
Publication statusPublished - Jan 13 2003
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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