Inherited Thyroid Cancer

Joycelyn Lee, Joanne Ngeow*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Thyroid cancer is common and has a steadily rising incidence [1]. Papillary thyroid cancer (PTC) is the most common histologic subtype, accounting for more than 90% of all thyroid cancers. Over 90% of thyroid cancers are sporadic, with less than 10% being familial [2]. Familial thyroid cancers can be divided into familial non-medullary thyroid cancers (FNMTC), or familial medullary thyroid cancers (FMTC) according to their cell of origin. Among FNMTC, about 5% are associated with defined syndromes and occur with a preponderance of non-thyroidal tumours [3] (see Diagram 14.1). The majority however are non-syndromic FNMTC. FMTC, on the other hand, is most commonly associated with multiple endocrine neoplasia (MEN). The presence of certain histological subtypes should also prompt consideration of familial thyroid cancer.

Original languageEnglish
Title of host publicationEvidence-Based Endocrine Surgery
PublisherSpringer Science+Business Media
Pages163-171
Number of pages9
ISBN (Electronic)9789811011245
ISBN (Print)9789811011238
DOIs
Publication statusPublished - Jan 1 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media Singapore 2018.

ASJC Scopus Subject Areas

  • General Medicine

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