TY - JOUR
T1 - InPhocus
T2 - Current State and Challenges of Phage Research in Singapore
AU - Verma, Navin Kumar
AU - Tan, Si Jia
AU - Chen, John
AU - Chen, Hanrong
AU - Ismail, Muhammad Hafiz
AU - Rice, Scott A.
AU - Bifani, Pablo
AU - Hariharan, Sukumar
AU - Paul, Vivek Daniel
AU - Sriram, Bharathi
AU - Dam, Linh Chi
AU - Chan, Chia Ching
AU - Ho, Peiying
AU - Goh, Boon Chong
AU - Chung, Shimin Jasmine
AU - Goh, Kenneth Choon Meng
AU - Thong, Shu Hua
AU - Kwa, Andrea Lay Hoon
AU - Ostrowski, Adam
AU - Aung, Thet Tun
AU - Razali, Halimah
AU - Low, Shermaine W.Y.
AU - Bhattacharyya, Mani Shankar
AU - Gautam, Hemant K.
AU - Lakshminarayanan, Rajamani
AU - Sicheritz-Pontén, Thomas
AU - Clokie, Martha R.J.
AU - Moreira, Wilfried
AU - Van Steensel, Maurice Adrianus Monique
N1 - Publisher Copyright:
© 2022, Mary Ann Liebert, Inc., publishers 2022.
PY - 2022/3
Y1 - 2022/3
N2 - Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore (NTU) and Yong Loo Lin School of Medicine, National University of Singapore (NUS) recently co-organized a virtual symposium on Bacteriophage and Bacteriophage-Derived Technologies, which was attended by more than 80 participants. Topics were discussed relating to phage life cycles, diversity, the roles of phages in biofilms and the human gut microbiome, engineered phage lysins to combat polymicrobial infections in wounds, and the challenges and prospects of clinical phage therapy. This perspective summarizes major points discussed during the symposium and new perceptions that emerged after the panel discussion.
AB - Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore (NTU) and Yong Loo Lin School of Medicine, National University of Singapore (NUS) recently co-organized a virtual symposium on Bacteriophage and Bacteriophage-Derived Technologies, which was attended by more than 80 participants. Topics were discussed relating to phage life cycles, diversity, the roles of phages in biofilms and the human gut microbiome, engineered phage lysins to combat polymicrobial infections in wounds, and the challenges and prospects of clinical phage therapy. This perspective summarizes major points discussed during the symposium and new perceptions that emerged after the panel discussion.
KW - antimicrobial resistance
KW - ectolysin
KW - filamentous phages
KW - metagenomics
KW - recombinant phage proteins
UR - http://www.scopus.com/inward/record.url?scp=85132015433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85132015433&partnerID=8YFLogxK
U2 - 10.1089/phage.2022.29028.nkv
DO - 10.1089/phage.2022.29028.nkv
M3 - Article
AN - SCOPUS:85132015433
SN - 2641-6530
VL - 3
SP - 6
EP - 11
JO - PHAGE: Therapy, Applications, and Research
JF - PHAGE: Therapy, Applications, and Research
IS - 1
ER -
