Interconversion of copper(II) to copper(I): Synthesis, characterization of copper(II) and copper(I) 2,2′-biquinoline complexes and their microbiological activity

Basem F. Ali*, Khaldoun Al-Sou'od, Nayef Al-Ja'ar, Ahmad Nassar, Mukarram H. Zaghal, Zaher Judeh, Rawhi Al-Far, Mahmoud Al-Refai, Mohamad Ibrahim, Kamal Mansi, K. H. Al-Obaidi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

The complexes [Cu(biq) 2]Cl 2 and [Cu(biq) 2]BF 4·biq (biq = 2,2′-biquinoline) have been prepared and characterized. The interconversion to copper(I) complex [Cu(biq) 2]BF 4·biq, from [Cu(biq) 2]Cl 2 has been established. The new complexes have been characterized by elemental analysis, conductivity and magnetic measurements, IR, UV-vis and 1H- and 13C-NMR spectroscopy. The X-ray analysis of the complex [Cu(biq) 2]BF 4·biq supports the assumption of the interconversion of copper(II) to copper(I) in this case. The crystal structure shows that geometry around the metal is severely distorted from T d, and displays many supramolecular motifs incorporating both hydrophobic (aryl⋯aryl) and hydrophilic (C-H⋯F) intermolecular interactions. The microbiological activity of the complexes against bacteria and fungi was found to be high against Candida albicans, and slight to moderate against bacteria. The antimicrobial activity of [Cu(biq) 2]BF 4·biq was slightly better than that observed for [Cu(biq) 2]Cl 2 against both bacteria and fungi.

Original languageEnglish
Pages (from-to)229-241
Number of pages13
JournalJournal of Coordination Chemistry
Volume59
Issue number2
DOIs
Publication statusPublished - Jan 20 2006
Externally publishedYes

ASJC Scopus Subject Areas

  • Physical and Theoretical Chemistry
  • Materials Chemistry

Keywords

  • (Aryl⋯aryl) and (C-H⋯F) intermolecular interactions
  • Biological activity
  • Copper complexes
  • Interconversion

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