Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene

Takuji Hatakeyama; Yoshiyuki Kondo; Yu Ichi Fujiwara; Hikaru Takaya; Shingo Ito; Eiichi Nakamura; Masaharu Nakamura

doi:10.1039/b820879d

Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene

Takuji Hatakeyama, Yoshiyuki Kondo, Yu Ichi Fujiwara, Hikaru Takaya, Shingo Ito, Eiichi Nakamura, Masaharu Nakamura^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

Abstract

A catalytic amount of 1,2-bis(diphenylphosphino)benzene (DPPBz) achieves selective cleavage of sp³-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to polyfluorinated aromatic compounds.

Original language	English
Pages (from-to)	1216-1218
Number of pages	3
Journal	Chemical Communications
Issue number	10
DOIs	https://doi.org/10.1039/b820879d
Publication status	Published - 2009
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "A catalytic amount of 1,2-bis(diphenylphosphino)benzene (DPPBz) achieves selective cleavage of sp3-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to polyfluorinated aromatic compounds.",

author = "Takuji Hatakeyama and Yoshiyuki Kondo and Fujiwara, {Yu Ichi} and Hikaru Takaya and Shingo Ito and Eiichi Nakamura and Masaharu Nakamura",

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AU - Hatakeyama, Takuji

AU - Kondo, Yoshiyuki

AU - Fujiwara, Yu Ichi

AU - Takaya, Hikaru

AU - Ito, Shingo

AU - Nakamura, Eiichi

AU - Nakamura, Masaharu

PY - 2009

Y1 - 2009

N2 - A catalytic amount of 1,2-bis(diphenylphosphino)benzene (DPPBz) achieves selective cleavage of sp3-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to polyfluorinated aromatic compounds.

AB - A catalytic amount of 1,2-bis(diphenylphosphino)benzene (DPPBz) achieves selective cleavage of sp3-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to polyfluorinated aromatic compounds.

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JO - Chemical Communications

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Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene

Abstract

ASJC Scopus Subject Areas

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