Magnet-PNIPA hydrogels for bioengineering applications

R. V. Ramanujan; K. L. Ang; S. Venkatraman

doi:10.1007/s10853-006-1064-x

Magnet-PNIPA hydrogels for bioengineering applications

R. V. Ramanujan, K. L. Ang, S. Venkatraman

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Temperature-sensitive Poly (N-isopropylacrylamide), PNIPA gels were synthesized with micron-sized iron and iron oxide (Fe₃O₄) particles to investigate their viability for hyperthermia applications. Induction heating of the magnetic hydrogels with varying concentration of magnetic powder was conducted at a frequency of 375 kHz for magnetic field strength varying from 1.7 kA/m (21 Oe) to 2.5 kA/m (31.4 Oe). It was observed that the maximum temperature induced in the magnetic hydrogels increased with the concentration of magnetic particles and magnetic field strength. The PNIPA gel underwent a collapse transition at 34 °C. It was found that a 2.5 wt.% Fe₃O₄ in PNIPA composite took 260 s to be heated to 45 °C under a magnetic field strength of 1.7 kA/m, the specific absorption rate (SAR) was found to be 1.83. SAR of iron oxide was found to be higher than the SAR of iron.

Original language	English
Pages (from-to)	1381-1387
Number of pages	7
Journal	Journal of Materials Science
Volume	44
Issue number	5
DOIs	https://doi.org/10.1007/s10853-006-1064-x
Publication status	Published - Mar 2009
Externally published	Yes

ASJC Scopus Subject Areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

Access to Document

10.1007/s10853-006-1064-x

Cite this

@article{b19788f6e7df4dbb907a2b438d5c5fe8,

title = "Magnet-PNIPA hydrogels for bioengineering applications",

abstract = "Temperature-sensitive Poly (N-isopropylacrylamide), PNIPA gels were synthesized with micron-sized iron and iron oxide (Fe3O4) particles to investigate their viability for hyperthermia applications. Induction heating of the magnetic hydrogels with varying concentration of magnetic powder was conducted at a frequency of 375 kHz for magnetic field strength varying from 1.7 kA/m (21 Oe) to 2.5 kA/m (31.4 Oe). It was observed that the maximum temperature induced in the magnetic hydrogels increased with the concentration of magnetic particles and magnetic field strength. The PNIPA gel underwent a collapse transition at 34 °C. It was found that a 2.5 wt.\% Fe3O4 in PNIPA composite took 260 s to be heated to 45 °C under a magnetic field strength of 1.7 kA/m, the specific absorption rate (SAR) was found to be 1.83. SAR of iron oxide was found to be higher than the SAR of iron.",

author = "Ramanujan, \{R. V.\} and Ang, \{K. L.\} and S. Venkatraman",

year = "2009",

month = mar,

doi = "10.1007/s10853-006-1064-x",

language = "English",

volume = "44",

pages = "1381--1387",

journal = "Journal of Materials Science",

issn = "0022-2461",

publisher = "Springer Netherlands",

number = "5",

}

TY - JOUR

T1 - Magnet-PNIPA hydrogels for bioengineering applications

AU - Ramanujan, R. V.

AU - Ang, K. L.

AU - Venkatraman, S.

PY - 2009/3

Y1 - 2009/3

N2 - Temperature-sensitive Poly (N-isopropylacrylamide), PNIPA gels were synthesized with micron-sized iron and iron oxide (Fe3O4) particles to investigate their viability for hyperthermia applications. Induction heating of the magnetic hydrogels with varying concentration of magnetic powder was conducted at a frequency of 375 kHz for magnetic field strength varying from 1.7 kA/m (21 Oe) to 2.5 kA/m (31.4 Oe). It was observed that the maximum temperature induced in the magnetic hydrogels increased with the concentration of magnetic particles and magnetic field strength. The PNIPA gel underwent a collapse transition at 34 °C. It was found that a 2.5 wt.% Fe3O4 in PNIPA composite took 260 s to be heated to 45 °C under a magnetic field strength of 1.7 kA/m, the specific absorption rate (SAR) was found to be 1.83. SAR of iron oxide was found to be higher than the SAR of iron.

AB - Temperature-sensitive Poly (N-isopropylacrylamide), PNIPA gels were synthesized with micron-sized iron and iron oxide (Fe3O4) particles to investigate their viability for hyperthermia applications. Induction heating of the magnetic hydrogels with varying concentration of magnetic powder was conducted at a frequency of 375 kHz for magnetic field strength varying from 1.7 kA/m (21 Oe) to 2.5 kA/m (31.4 Oe). It was observed that the maximum temperature induced in the magnetic hydrogels increased with the concentration of magnetic particles and magnetic field strength. The PNIPA gel underwent a collapse transition at 34 °C. It was found that a 2.5 wt.% Fe3O4 in PNIPA composite took 260 s to be heated to 45 °C under a magnetic field strength of 1.7 kA/m, the specific absorption rate (SAR) was found to be 1.83. SAR of iron oxide was found to be higher than the SAR of iron.

UR - http://www.scopus.com/inward/record.url?scp=60449116293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=60449116293&partnerID=8YFLogxK

U2 - 10.1007/s10853-006-1064-x

DO - 10.1007/s10853-006-1064-x

M3 - Article

AN - SCOPUS:60449116293

SN - 0022-2461

VL - 44

SP - 1381

EP - 1387

JO - Journal of Materials Science

JF - Journal of Materials Science

IS - 5

ER -

Magnet-PNIPA hydrogels for bioengineering applications

Abstract

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this