Manganese-Catalyzed Ring-Opening Coupling Reactions of Cyclopropanols with Enones

Yong Hui Zhang; Wen Wei Zhang; Ze Yu Zhang; Kai Zhao; Teck Peng Loh

doi:10.1021/acs.orglett.9b01703

Manganese-Catalyzed Ring-Opening Coupling Reactions of Cyclopropanols with Enones

Yong Hui Zhang, Wen Wei Zhang, Ze Yu Zhang, Kai Zhao^*, Teck Peng Loh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

A manganese-catalyzed ring-opening coupling reaction of cyclopropanols with enones for the facile and efficient preparation of 1,6-diketones is described. A wide array of synthetically important 1,6-diketones bearing manifold functional groups are obtained with up to 93% yield. These reactions feature broad substrate scopes, environmentally benign conditions, inexpensive catalyst, and operational simplicity.

Original language	English
Pages (from-to)	5101-5105
Number of pages	5
Journal	Organic Letters
Volume	21
Issue number	13
DOIs	https://doi.org/10.1021/acs.orglett.9b01703
Publication status	Published - Jun 17 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
Copyright © 2019 American Chemical Society.

ASJC Scopus Subject Areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/acs.orglett.9b01703

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AB - A manganese-catalyzed ring-opening coupling reaction of cyclopropanols with enones for the facile and efficient preparation of 1,6-diketones is described. A wide array of synthetically important 1,6-diketones bearing manifold functional groups are obtained with up to 93% yield. These reactions feature broad substrate scopes, environmentally benign conditions, inexpensive catalyst, and operational simplicity.

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Manganese-Catalyzed Ring-Opening Coupling Reactions of Cyclopropanols with Enones

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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