Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging

Kien Voon Kong; Zhiyong Lam; Wenda Douglas Goh; Weng Kee Leong; Malini Olivo

doi:10.1002/anie.201204349

Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging

Kien Voon Kong^*, Zhiyong Lam, Wenda Douglas Goh, Weng Kee Leong, Malini Olivo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

104 Citations (Scopus)

Abstract

Conjugates of organometallic osmium carbonyl clusters and gold nanoparticles (see picture) show a strong carbonyl signal in surface-enhanced Raman spectroscopy. The ease of bio-functionalization and the high stability and good dispersibility in aqueous solution make these conjugates excellent candidates for biomedical applications, as demonstrated by live-cell imaging with the carbonyl signals of OM-NP(PEG)-L conjugates.

Original language	English
Pages (from-to)	9796-9799
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	39
DOIs	https://doi.org/10.1002/anie.201204349
Publication status	Published - Sept 24 2012
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
General Chemistry

Keywords

cluster compounds
epidermoid carcinoma
imaging agents
metal carbonyl compounds
nanoparticles

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10.1002/anie.201204349

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abstract = "Conjugates of organometallic osmium carbonyl clusters and gold nanoparticles (see picture) show a strong carbonyl signal in surface-enhanced Raman spectroscopy. The ease of bio-functionalization and the high stability and good dispersibility in aqueous solution make these conjugates excellent candidates for biomedical applications, as demonstrated by live-cell imaging with the carbonyl signals of OM-NP(PEG)-L conjugates.",

keywords = "cluster compounds, epidermoid carcinoma, imaging agents, metal carbonyl compounds, nanoparticles",

author = "Kong, {Kien Voon} and Zhiyong Lam and Goh, {Wenda Douglas} and Leong, {Weng Kee} and Malini Olivo",

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AU - Kong, Kien Voon

AU - Lam, Zhiyong

AU - Goh, Wenda Douglas

AU - Leong, Weng Kee

AU - Olivo, Malini

PY - 2012/9/24

Y1 - 2012/9/24

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AB - Conjugates of organometallic osmium carbonyl clusters and gold nanoparticles (see picture) show a strong carbonyl signal in surface-enhanced Raman spectroscopy. The ease of bio-functionalization and the high stability and good dispersibility in aqueous solution make these conjugates excellent candidates for biomedical applications, as demonstrated by live-cell imaging with the carbonyl signals of OM-NP(PEG)-L conjugates.

KW - cluster compounds

KW - epidermoid carcinoma

KW - imaging agents

KW - metal carbonyl compounds

KW - nanoparticles

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ER -

Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging

Abstract

ASJC Scopus Subject Areas

Keywords

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