Molecular mimicry between Helicobacter pylori and the host

Ben J. Appelmelk; Riccardo Negrini; Anthony P. Moran; Ernst J. Kuipers

doi:10.1016/S0966-842X(96)10084-6

Molecular mimicry between Helicobacter pylori and the host

Ben J. Appelmelk^*, Riccardo Negrini, Anthony P. Moran, Ernst J. Kuipers

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

139 Citations (Scopus)

Abstract

Helicobacter pylori lipopolysaccharide (LPS) expresses Lewis x and Lewis y blood group antigens that are identical to those occurring in the human gastric mucosa. During infection, antibodies against LPS, which bind to host Lewis antigens, may be induced. These consequently recognize gastric glycoprotein targets and cause autoimmune inflammation.

Original language	English
Pages (from-to)	70-73
Number of pages	4
Journal	Trends in Microbiology
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/S0966-842X(96)10084-6
Publication status	Published - Feb 1997
Externally published	Yes

ASJC Scopus Subject Areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0966-842X(96)10084-6

Cite this

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title = "Molecular mimicry between Helicobacter pylori and the host",

abstract = "Helicobacter pylori lipopolysaccharide (LPS) expresses Lewis x and Lewis y blood group antigens that are identical to those occurring in the human gastric mucosa. During infection, antibodies against LPS, which bind to host Lewis antigens, may be induced. These consequently recognize gastric glycoprotein targets and cause autoimmune inflammation.",

author = "Appelmelk, {Ben J.} and Riccardo Negrini and Moran, {Anthony P.} and Kuipers, {Ernst J.}",

year = "1997",

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language = "English",

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journal = "Trends in Microbiology",

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TY - JOUR

T1 - Molecular mimicry between Helicobacter pylori and the host

AU - Appelmelk, Ben J.

AU - Negrini, Riccardo

AU - Moran, Anthony P.

AU - Kuipers, Ernst J.

PY - 1997/2

Y1 - 1997/2

N2 - Helicobacter pylori lipopolysaccharide (LPS) expresses Lewis x and Lewis y blood group antigens that are identical to those occurring in the human gastric mucosa. During infection, antibodies against LPS, which bind to host Lewis antigens, may be induced. These consequently recognize gastric glycoprotein targets and cause autoimmune inflammation.

AB - Helicobacter pylori lipopolysaccharide (LPS) expresses Lewis x and Lewis y blood group antigens that are identical to those occurring in the human gastric mucosa. During infection, antibodies against LPS, which bind to host Lewis antigens, may be induced. These consequently recognize gastric glycoprotein targets and cause autoimmune inflammation.

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UR - http://www.scopus.com/inward/citedby.url?scp=0031081613&partnerID=8YFLogxK

U2 - 10.1016/S0966-842X(96)10084-6

DO - 10.1016/S0966-842X(96)10084-6

M3 - Review article

C2 - 9108933

AN - SCOPUS:0031081613

SN - 0966-842X

VL - 5

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EP - 73

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 2

ER -

Molecular mimicry between Helicobacter pylori and the host

Abstract

ASJC Scopus Subject Areas

UN SDGs

Access to Document

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