Abstract
Small molecule metabolites secreted by pathological processes can act as molecular biomarkers for clinical diagnosis. In vitro detection of the metabolites such as glucose and reactive oxygen species is of great significance for precise screening, monitoring and prognosis of metabolic disorders and relevant diseases such as cancer, and has been under intense research and development in clinical chemistry and molecular diagnostics. In this review, we summarize recent developments in nanomaterial based electrochemical (bio)sensors for in vitro detection of glucose and reactive oxygen species and the progress in utilizing lightweight and flexible electrodes and micro/nanoscale electrodes for flexible and miniaturized sensors.
| Original language | English |
|---|---|
| Pages (from-to) | 234-249 |
| Number of pages | 16 |
| Journal | Biotechnology Advances |
| Volume | 34 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1 2016 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2016 Elsevier Inc.
ASJC Scopus Subject Areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology
Keywords
- Electrochemical (EC) sensors
- Glucose sensor
- In vitro diagnostics
- Metabolic diseases
- Nanomaterials (NMs)
- Reactive oxygen species
