Nederlandse studie naar de beste behandelstrategie bij patiënten met een eerste of tweede oesofagus- of maagvaricesbloeding: De TIPS-TRUE-trial

H. R. Van Buuren; A. Wils; E. A.J. Rauws; B. Van Hoek; J. P.H. Drenth; E. J. Kuipers; P. M.T. Pattynama

Nederlandse studie naar de beste behandelstrategie bij patiënten met een eerste of tweede oesofagus- of maagvaricesbloeding: De TIPS-TRUE-trial

Translated title of the contribution: Dutch study on the optimal treatment strategy for patients with a first or second occurrence of gastro-oesophageal variceal bleeding: The TIPS-TRUE trial

H. R. Van Buuren, A. Wils, E. A.J. Rauws, B. Van Hoek, J. P.H. Drenth, E. J. Kuipers, P. M.T. Pattynama

Research output: Contribution to journal › Short survey › peer-review

2 Citations (Scopus)

Abstract

The main options for secondary prevention of gastrooesophageal variceal bleeding are endoscopic therapy and treatment with propranolol. Creation of a transjugular intrahepatic portosystemic shunt (TIPS) is currently considered a valuable secondary 'rescue' treatment when other therapies fail. Recent data suggest that the use of covered stents markedly increases the efficacy of TIPS, compared with conventional uncovered stents. Therefore, a multicentre randomised trial was designed to compare the effects of TIPS using covered stents with those of endoscopic therapy plus propranolol in patients with a first or second episode of gastro-oesophageal variceal bleeding. TIPS will be performed in 4 university centres with relevant expertise. The trial will hopefully gain nationwide support, and all centres in the Netherlands are cordially invited to participate.

Translated title of the contribution	Dutch study on the optimal treatment strategy for patients with a first or second occurrence of gastro-oesophageal variceal bleeding: The TIPS-TRUE trial
Original language	Dutch (Belgium)
Pages (from-to)	643-645
Number of pages	3
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	152
Issue number	11
Publication status	Published - Mar 15 2008
Externally published	Yes

ASJC Scopus Subject Areas

General Medicine

Cite this

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title = "Nederlandse studie naar de beste behandelstrategie bij pati{\"e}nten met een eerste of tweede oesofagus- of maagvaricesbloeding: De TIPS-TRUE-trial",

abstract = "The main options for secondary prevention of gastrooesophageal variceal bleeding are endoscopic therapy and treatment with propranolol. Creation of a transjugular intrahepatic portosystemic shunt (TIPS) is currently considered a valuable secondary 'rescue' treatment when other therapies fail. Recent data suggest that the use of covered stents markedly increases the efficacy of TIPS, compared with conventional uncovered stents. Therefore, a multicentre randomised trial was designed to compare the effects of TIPS using covered stents with those of endoscopic therapy plus propranolol in patients with a first or second episode of gastro-oesophageal variceal bleeding. TIPS will be performed in 4 university centres with relevant expertise. The trial will hopefully gain nationwide support, and all centres in the Netherlands are cordially invited to participate.",

author = "{Van Buuren}, {H. R.} and A. Wils and Rauws, {E. A.J.} and {Van Hoek}, B. and Drenth, {J. P.H.} and Kuipers, {E. J.} and Pattynama, {P. M.T.}",

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T2 - De TIPS-TRUE-trial

AU - Van Buuren, H. R.

AU - Wils, A.

AU - Rauws, E. A.J.

AU - Van Hoek, B.

AU - Drenth, J. P.H.

AU - Kuipers, E. J.

AU - Pattynama, P. M.T.

PY - 2008/3/15

Y1 - 2008/3/15

N2 - The main options for secondary prevention of gastrooesophageal variceal bleeding are endoscopic therapy and treatment with propranolol. Creation of a transjugular intrahepatic portosystemic shunt (TIPS) is currently considered a valuable secondary 'rescue' treatment when other therapies fail. Recent data suggest that the use of covered stents markedly increases the efficacy of TIPS, compared with conventional uncovered stents. Therefore, a multicentre randomised trial was designed to compare the effects of TIPS using covered stents with those of endoscopic therapy plus propranolol in patients with a first or second episode of gastro-oesophageal variceal bleeding. TIPS will be performed in 4 university centres with relevant expertise. The trial will hopefully gain nationwide support, and all centres in the Netherlands are cordially invited to participate.

AB - The main options for secondary prevention of gastrooesophageal variceal bleeding are endoscopic therapy and treatment with propranolol. Creation of a transjugular intrahepatic portosystemic shunt (TIPS) is currently considered a valuable secondary 'rescue' treatment when other therapies fail. Recent data suggest that the use of covered stents markedly increases the efficacy of TIPS, compared with conventional uncovered stents. Therefore, a multicentre randomised trial was designed to compare the effects of TIPS using covered stents with those of endoscopic therapy plus propranolol in patients with a first or second episode of gastro-oesophageal variceal bleeding. TIPS will be performed in 4 university centres with relevant expertise. The trial will hopefully gain nationwide support, and all centres in the Netherlands are cordially invited to participate.

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M3 - Short survey

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JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

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ER -

Nederlandse studie naar de beste behandelstrategie bij patiënten met een eerste of tweede oesofagus- of maagvaricesbloeding: De TIPS-TRUE-trial

Abstract

ASJC Scopus Subject Areas

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