Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters

Jianrong Steve Zhou; Siyu Guo; Xiaohu Zhao; Yonggui Robin Chi

doi:10.1039/d1cc05257h

Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters

Jianrong Steve Zhou^*, Siyu Guo, Xiaohu Zhao, Yonggui Robin Chi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.

Original language	English
Pages (from-to)	11501-11504
Number of pages	4
Journal	Chemical Communications
Volume	57
Issue number	87
DOIs	https://doi.org/10.1039/d1cc05257h
Publication status	Published - Nov 11 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 The Royal Society of Chemistry.

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/d1cc05257h

Cite this

@article{c64eb504ec264bfdbd7d062e3423fa8f,

title = "Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters",

abstract = "Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.",

author = "Zhou, {Jianrong Steve} and Siyu Guo and Xiaohu Zhao and Chi, {Yonggui Robin}",

note = "Publisher Copyright: {\textcopyright} 2021 The Royal Society of Chemistry.",

year = "2021",

month = nov,

day = "11",

doi = "10.1039/d1cc05257h",

language = "English",

volume = "57",

pages = "11501--11504",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "87",

}

TY - JOUR

T1 - Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters

AU - Zhou, Jianrong Steve

AU - Guo, Siyu

AU - Zhao, Xiaohu

AU - Chi, Yonggui Robin

PY - 2021/11/11

Y1 - 2021/11/11

N2 - Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.

AB - Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.

UR - http://www.scopus.com/inward/record.url?scp=85118829375&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85118829375&partnerID=8YFLogxK

U2 - 10.1039/d1cc05257h

DO - 10.1039/d1cc05257h

M3 - Article

C2 - 34652359

AN - SCOPUS:85118829375

SN - 1359-7345

VL - 57

SP - 11501

EP - 11504

JO - Chemical Communications

JF - Chemical Communications

IS - 87

ER -

Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this