Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

Teck Peng Loh; Lin Li Wei

doi:10.1016/S0040-4039(97)10478-6

Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

Teck Peng Loh^*, Lin Li Wei

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

163 Citations (Scopus)

Abstract

Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give β-amino ketones and esters in moderate to good yields.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	3-4
DOIs	https://doi.org/10.1016/S0040-4039(97)10478-6
Publication status	Published - Jan 15 1998
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters",

abstract = "Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give β-amino ketones and esters in moderate to good yields.",

author = "Loh, {Teck Peng} and Wei, {Lin Li}",

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T2 - Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

AU - Loh, Teck Peng

AU - Wei, Lin Li

PY - 1998/1/15

Y1 - 1998/1/15

N2 - Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give β-amino ketones and esters in moderate to good yields.

AB - Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give β-amino ketones and esters in moderate to good yields.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 3-4

ER -

Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

Abstract

ASJC Scopus Subject Areas

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