One-pot chemoenzymatic syntheses of enantiomerically-enriched O-acetyl cyanohydrins from aldehydes in ionic liquid

Zhi Liang Shen; Wei Juan Zhou; Ya Ting Liu; Shun Jun Ji; Teck Peng Loh

doi:10.1039/b717235d

One-pot chemoenzymatic syntheses of enantiomerically-enriched O-acetyl cyanohydrins from aldehydes in ionic liquid

Zhi Liang Shen, Wei Juan Zhou, Ya Ting Liu, Shun Jun Ji, Teck Peng Loh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

A practical and efficient method for the synthesis of optically active O-acetyl cyanohydrins via one-pot lipase-catalyzed kinetic resolution of the in situ generated racemic cyanohydrins or O-acetyl cyanohydrins using an ionic liquid as both reaction media and promoter has been described.

Original language	English
Pages (from-to)	283-228
Number of pages	56
Journal	Green Chemistry
Volume	10
Issue number	3
DOIs	https://doi.org/10.1039/b717235d
Publication status	Published - Mar 1 2008
Externally published	Yes

ASJC Scopus Subject Areas

Environmental Chemistry
Pollution

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10.1039/b717235d

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abstract = "A practical and efficient method for the synthesis of optically active O-acetyl cyanohydrins via one-pot lipase-catalyzed kinetic resolution of the in situ generated racemic cyanohydrins or O-acetyl cyanohydrins using an ionic liquid as both reaction media and promoter has been described.",

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AU - Shen, Zhi Liang

AU - Zhou, Wei Juan

AU - Liu, Ya Ting

AU - Ji, Shun Jun

AU - Loh, Teck Peng

PY - 2008/3/1

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AB - A practical and efficient method for the synthesis of optically active O-acetyl cyanohydrins via one-pot lipase-catalyzed kinetic resolution of the in situ generated racemic cyanohydrins or O-acetyl cyanohydrins using an ionic liquid as both reaction media and promoter has been described.

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One-pot chemoenzymatic syntheses of enantiomerically-enriched O-acetyl cyanohydrins from aldehydes in ionic liquid

Abstract

ASJC Scopus Subject Areas

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