Organometallic carbonyl clusters: A new class of contrast agents for photoacoustic cerebral vascular imaging

Kien Voon Kong; Lun De Liao; Zhiyong Lam; Nitish V. Thakor; Weng Kee Leong; Malini Olivo

doi:10.1039/c3cc48529c

Organometallic carbonyl clusters: A new class of contrast agents for photoacoustic cerebral vascular imaging

Kien Voon Kong, Lun De Liao, Zhiyong Lam, Nitish V. Thakor, Weng Kee Leong, Malini Olivo

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy.

Original language	English
Pages (from-to)	2601-2603
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	20
DOIs	https://doi.org/10.1039/c3cc48529c
Publication status	Published - Feb 11 2014
Externally published	Yes

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy.",

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AU - Kong, Kien Voon

AU - Liao, Lun De

AU - Lam, Zhiyong

AU - Thakor, Nitish V.

AU - Leong, Weng Kee

AU - Olivo, Malini

PY - 2014/2/11

Y1 - 2014/2/11

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AB - We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy.

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Organometallic carbonyl clusters: A new class of contrast agents for photoacoustic cerebral vascular imaging

Abstract

ASJC Scopus Subject Areas

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