Palladium-catalyzed direct arylation of cyclic enamides with aryl silanes by sp2 C-H activation

Hai Zhou; Yun He Xu; Wan Jun Chung; Teck Peng Loh

doi:10.1002/anie.200901884

Palladium-catalyzed direct arylation of cyclic enamides with aryl silanes by sp² C-H activation

Hai Zhou^*, Yun He Xu, Wan Jun Chung, Teck Peng Loh

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

196 Citations (Scopus)

Abstract

It does get in! A fluoride-assisted direct cross-coupling of cyclic enamides with trialkoxy aryl silanes by a palladiumcatalyzed C-H activation leads to a wide range of enamides in yields of up to 95%.

Original language	English
Pages (from-to)	5355-5357
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	29
DOIs	https://doi.org/10.1002/anie.200901884
Publication status	Published - Jul 6 2009
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
General Chemistry

Keywords

Arylation
C-C coupling
C-H activation
Enamides
Palladium

Access to Document

10.1002/anie.200901884

Cite this

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abstract = "It does get in! A fluoride-assisted direct cross-coupling of cyclic enamides with trialkoxy aryl silanes by a palladiumcatalyzed C-H activation leads to a wide range of enamides in yields of up to 95%.",

keywords = "Arylation, C-C coupling, C-H activation, Enamides, Palladium",

author = "Hai Zhou and Xu, {Yun He} and Chung, {Wan Jun} and Loh, {Teck Peng}",

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AU - Zhou, Hai

AU - Xu, Yun He

AU - Chung, Wan Jun

AU - Loh, Teck Peng

PY - 2009/7/6

Y1 - 2009/7/6

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AB - It does get in! A fluoride-assisted direct cross-coupling of cyclic enamides with trialkoxy aryl silanes by a palladiumcatalyzed C-H activation leads to a wide range of enamides in yields of up to 95%.

KW - Arylation

KW - C-C coupling

KW - C-H activation

KW - Enamides

KW - Palladium

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