Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents

Paul Kumar Upputuri; Yuyan Jiang; Kanyi Pu; Manojit Pramanik

doi:10.1117/12.2287084

Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents

Paul Kumar Upputuri, Yuyan Jiang, Kanyi Pu, Manojit Pramanik

Nanyang Technological University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Photoacoustic (PA) imaging is a promising imaging modality for both preclinical research and clinical practices. Laser wavelengths in the first near infrared window (NIR-I, 650-950 nm) have been widely used for photoacoustic imaging. As compared with NIR-I window, scattering of photons by biological tissues is largely reduced in the second NIR (NIR-II) window, leading to enhanced imaging fidelity. However, the lack of biocompatible NIR-II absorbing exogenous agents prevented the use of this window for in vivo imaging. In recent years, few studies have been reported on photoacoustic imaging in NIR-II window using exogenous contrast agents. In this work, we discuss the recent work on PA imaging using 1064 nm wavelength, the fundamental of Nd:YAG laser, as an excitation wavelength. The PA imaging at 1064 nm is advantageous because of the low and homogeneous signal from tissue background, enabling high contrast in PA imaging when NIR-II absorbing contrast agents are employed.

Original language	English
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2018
Editors	Lihong V. Wang, Alexander A. Oraevsky
Publisher	SPIE
ISBN (Electronic)	9781510614734
DOIs	https://doi.org/10.1117/12.2287084
Publication status	Published - 2018
Externally published	Yes
Event	Photons Plus Ultrasound: Imaging and Sensing 2018 - San Francisco, United States Duration: Jan 28 2018 → Feb 1 2018

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10494
ISSN (Print)	1605-7422

Conference

Conference	Photons Plus Ultrasound: Imaging and Sensing 2018
Country/Territory	United States
City	San Francisco
Period	1/28/18 → 2/1/18

Bibliographical note

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Keywords

contrast agent
in vivo imaging
photoacoustic imaging
second near-infrared window

Access to Document

10.1117/12.2287084

Cite this

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title = "Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents",

abstract = "Photoacoustic (PA) imaging is a promising imaging modality for both preclinical research and clinical practices. Laser wavelengths in the first near infrared window (NIR-I, 650-950 nm) have been widely used for photoacoustic imaging. As compared with NIR-I window, scattering of photons by biological tissues is largely reduced in the second NIR (NIR-II) window, leading to enhanced imaging fidelity. However, the lack of biocompatible NIR-II absorbing exogenous agents prevented the use of this window for in vivo imaging. In recent years, few studies have been reported on photoacoustic imaging in NIR-II window using exogenous contrast agents. In this work, we discuss the recent work on PA imaging using 1064 nm wavelength, the fundamental of Nd:YAG laser, as an excitation wavelength. The PA imaging at 1064 nm is advantageous because of the low and homogeneous signal from tissue background, enabling high contrast in PA imaging when NIR-II absorbing contrast agents are employed.",

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author = "Upputuri, {Paul Kumar} and Yuyan Jiang and Kanyi Pu and Manojit Pramanik",

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year = "2018",

doi = "10.1117/12.2287084",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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Upputuri, PK, Jiang, Y, Pu, K & Pramanik, M 2018, Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents. in LV Wang & AA Oraevsky (eds), Photons Plus Ultrasound: Imaging and Sensing 2018., 104943K, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10494, SPIE, Photons Plus Ultrasound: Imaging and Sensing 2018, San Francisco, United States, 1/28/18. https://doi.org/10.1117/12.2287084

Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents. / Upputuri, Paul Kumar; Jiang, Yuyan; Pu, Kanyi et al.
Photons Plus Ultrasound: Imaging and Sensing 2018. ed. / Lihong V. Wang; Alexander A. Oraevsky. SPIE, 2018. 104943K (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10494).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents

AU - Upputuri, Paul Kumar

AU - Jiang, Yuyan

AU - Pu, Kanyi

AU - Pramanik, Manojit

N1 - Publisher Copyright: © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

PY - 2018

Y1 - 2018

N2 - Photoacoustic (PA) imaging is a promising imaging modality for both preclinical research and clinical practices. Laser wavelengths in the first near infrared window (NIR-I, 650-950 nm) have been widely used for photoacoustic imaging. As compared with NIR-I window, scattering of photons by biological tissues is largely reduced in the second NIR (NIR-II) window, leading to enhanced imaging fidelity. However, the lack of biocompatible NIR-II absorbing exogenous agents prevented the use of this window for in vivo imaging. In recent years, few studies have been reported on photoacoustic imaging in NIR-II window using exogenous contrast agents. In this work, we discuss the recent work on PA imaging using 1064 nm wavelength, the fundamental of Nd:YAG laser, as an excitation wavelength. The PA imaging at 1064 nm is advantageous because of the low and homogeneous signal from tissue background, enabling high contrast in PA imaging when NIR-II absorbing contrast agents are employed.

AB - Photoacoustic (PA) imaging is a promising imaging modality for both preclinical research and clinical practices. Laser wavelengths in the first near infrared window (NIR-I, 650-950 nm) have been widely used for photoacoustic imaging. As compared with NIR-I window, scattering of photons by biological tissues is largely reduced in the second NIR (NIR-II) window, leading to enhanced imaging fidelity. However, the lack of biocompatible NIR-II absorbing exogenous agents prevented the use of this window for in vivo imaging. In recent years, few studies have been reported on photoacoustic imaging in NIR-II window using exogenous contrast agents. In this work, we discuss the recent work on PA imaging using 1064 nm wavelength, the fundamental of Nd:YAG laser, as an excitation wavelength. The PA imaging at 1064 nm is advantageous because of the low and homogeneous signal from tissue background, enabling high contrast in PA imaging when NIR-II absorbing contrast agents are employed.

KW - contrast agent

KW - in vivo imaging

KW - photoacoustic imaging

KW - second near-infrared window

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ER -

Photoacoustic imaging at 1064nm wavelength with exogenous contrast agents

Abstract

Publication series

Conference

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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