@inbook{4ea78c5571664651b324bdaba02d0278,
title = "Proteomic analysis of vascular smooth muscle cells with S- and R-Enantiomers of atenolol by iTRAQ and LC-MS/MS",
abstract = "The term {"}proteome{"} was fi rst introduced by referring to the complete determination of proteins expressed in a given cell, tissue, or organism. In HPLC-based proteomics technique, the mixture of the cleaved peptides are bonded, separated sequentially on the multidimensional columns based on charge or hydrophobicity of the ionized analytes, and then eluted into the MS for identi fi cation. Among the developed stable isotope-based quanti fi cation methods, iTRAQ has recently gained popularity as its simple iTRAQ labeling procedures and up to eight labeled samples examined in a single experiment.",
keywords = "Atenolol, Cardiac adrenoreceptors, Chiral drug, ITRAQ, LC-MS/MS, Proteomics",
author = "Jianhua Zhang and Jiahua Shi and Lee, {Benedict Jia Hong} and Liwei Chen and Tan, {Kee Yang} and Xiaoling Tang and Tan, {Jane Yi Lin} and Xiang Li and Huixing Feng and Chen, {Wei Ning}",
year = "2013",
doi = "10.1007/978-1-62703-405-0_4",
language = "English",
isbn = "9781627034043",
series = "Methods in Molecular Biology",
pages = "45--52",
editor = "Fernando Vivanco",
booktitle = "Vascular Proteomics",
}