TY - JOUR
T1 - Quality of life in participants of a CRC screening program
AU - Kapidzic, A.
AU - Korfage, I. J.
AU - Van Dam, L.
AU - Van Roon, A. H.C.
AU - Reijerink, J. C.I.Y.
AU - Zauber, A. G.
AU - Van Ballegooijen, M.
AU - Kuipers, E. J.
AU - Van Leerdam, M. E.
PY - 2012/10/9
Y1 - 2012/10/9
N2 - Background: Little is known about the effect of participating in a colorectal cancer (CRC) screening programme on quality of life (QOL), neither for participants with a negative nor for those with a positive test result. These findings, however, are important to evaluate the impact of CRC screening. Methods: Participants from CRC screening trials were sent a questionnaire, which included validated measures on generic health-related QOL, generic anxiety and screen-specific anxiety. Both faecal immunochemical test (FIT) and flexible sigmoidoscopy (FS) participants, either with negative or positive test results, were addressed. Results: The response rate was 73% (1289 out of 1772) for FIT and 78% (536 out of 689) for FS participants, with mean ages varying from 63-66 years. Positive FIT participants had worse physical (PCS-12, 47.1 vs 48.3, P=0.02), but equal mental QOL scores (MCS-12, 51.1 vs 51.6, P=0.26). Positive and negative FS participants had similar QOL scores. Both FIT and FS participants with a positive test result reported more screen-specific anxiety than negative FIT and FS participants. Positive and negative FS participants had similar generic anxiety scores. Conclusion: Our findings indicate that the burden of participating in CRC screening may be limited. Conducting a prospective study to confirm these results is recommended.
AB - Background: Little is known about the effect of participating in a colorectal cancer (CRC) screening programme on quality of life (QOL), neither for participants with a negative nor for those with a positive test result. These findings, however, are important to evaluate the impact of CRC screening. Methods: Participants from CRC screening trials were sent a questionnaire, which included validated measures on generic health-related QOL, generic anxiety and screen-specific anxiety. Both faecal immunochemical test (FIT) and flexible sigmoidoscopy (FS) participants, either with negative or positive test results, were addressed. Results: The response rate was 73% (1289 out of 1772) for FIT and 78% (536 out of 689) for FS participants, with mean ages varying from 63-66 years. Positive FIT participants had worse physical (PCS-12, 47.1 vs 48.3, P=0.02), but equal mental QOL scores (MCS-12, 51.1 vs 51.6, P=0.26). Positive and negative FS participants had similar QOL scores. Both FIT and FS participants with a positive test result reported more screen-specific anxiety than negative FIT and FS participants. Positive and negative FS participants had similar generic anxiety scores. Conclusion: Our findings indicate that the burden of participating in CRC screening may be limited. Conducting a prospective study to confirm these results is recommended.
KW - Colorectal cancer screening
KW - Faecal immunochemical test
KW - Flexible sigmoidoscopy
KW - Quality of life
KW - Screen-specific anxiety
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U2 - 10.1038/bjc.2012.386
DO - 10.1038/bjc.2012.386
M3 - Article
C2 - 22955850
AN - SCOPUS:84867396104
SN - 0007-0920
VL - 107
SP - 1295
EP - 1301
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 8
ER -
