Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1

Sophie Bleves, Chantal Soscia, Patricia Nogueira-Orlandi, Andrée Lazdunski, Alain Filloux*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

121 Citations (Scopus)

Abstract

A systematic analysis of the type III secretion (T3S) genes of Pseudomonas aeruginosa strain PAO1 revealed that they are under quorum-sensing control. This observation was supported by the down-regulation of the T3S regulon in the presence of RhlR-C4HSL and the corresponding advanced secretion of ExoS in a rhlI mutant.

Original languageEnglish
Pages (from-to)3898-3902
Number of pages5
JournalJournal of Bacteriology
Volume187
Issue number11
DOIs
Publication statusPublished - Jun 2005
Externally publishedYes

ASJC Scopus Subject Areas

  • Microbiology
  • Molecular Biology

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