Recent developments in sample preparation and data pre-treatment in metabonomics research

Ning Li; Yi Peng Song; Huiru Tang; Yulan Wang

doi:10.1016/j.abb.2015.08.024

Recent developments in sample preparation and data pre-treatment in metabonomics research

Ning Li, Yi Peng Song, Huiru Tang, Yulan Wang^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

39 Citations (Scopus)

Abstract

Metabonomics is a powerful approach for biomarker discovery and an effective tool for pinpointing endpoint metabolic effects of external stimuli, such as pathogens and disease development. Due to its wide applications, metabonomics is required to deal with various biological samples of different properties. Hence sample preparation and corresponding data pre-treatment become important factors in ensuring validity of an investigation. In this review, we summarize some recent developments in metabonomics sample preparation and data-pretreatment procedures.

Original language	English
Pages (from-to)	4-9
Number of pages	6
Journal	Archives of Biochemistry and Biophysics
Volume	589
DOIs	https://doi.org/10.1016/j.abb.2015.08.024
Publication status	Published - Jan 1 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

ASJC Scopus Subject Areas

Biophysics
Biochemistry
Molecular Biology

Keywords

Data pre-treatment
Metabonomics research
Sample preparation

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10.1016/j.abb.2015.08.024

Cite this

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abstract = "Metabonomics is a powerful approach for biomarker discovery and an effective tool for pinpointing endpoint metabolic effects of external stimuli, such as pathogens and disease development. Due to its wide applications, metabonomics is required to deal with various biological samples of different properties. Hence sample preparation and corresponding data pre-treatment become important factors in ensuring validity of an investigation. In this review, we summarize some recent developments in metabonomics sample preparation and data-pretreatment procedures.",

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AU - Tang, Huiru

AU - Wang, Yulan

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Y1 - 2016/1/1

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AB - Metabonomics is a powerful approach for biomarker discovery and an effective tool for pinpointing endpoint metabolic effects of external stimuli, such as pathogens and disease development. Due to its wide applications, metabonomics is required to deal with various biological samples of different properties. Hence sample preparation and corresponding data pre-treatment become important factors in ensuring validity of an investigation. In this review, we summarize some recent developments in metabonomics sample preparation and data-pretreatment procedures.

KW - Data pre-treatment

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JF - Archives of Biochemistry and Biophysics

ER -

Recent developments in sample preparation and data pre-treatment in metabonomics research

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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