Reductive Desulfonylation of Sulfonamides under Polysulfide Anions Photocatalysis

Zixuan Feng, Eugene Yew Kun Tan, Shunsuke Chiba

Research output: Contribution to journalArticlepeer-review

Abstract

We demonstrate that polysulfide anions are capable of catalyzing desulfonylation of sulfonamides having a series of aryl and alkyl substituents in the presence of potassium formate under irradiation with visible light. The developed protocol is operationally concise and cost-effective, representing a practical and sustainable synthetic tool for desulfonylation and expanding the chemical space in secondary amine synthesis.

Original languageEnglish
Pages (from-to)4026-4031
Number of pages6
JournalOrganic Letters
Volume27
Issue number15
DOIs
Publication statusPublished - Apr 18 2025
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Reductive Desulfonylation of Sulfonamides under Polysulfide Anions Photocatalysis'. Together they form a unique fingerprint.

Cite this