Semiconducting polymer nanoprobe for in vivo imaging of reactive oxygen and nitrogen species

Kanyi Pu, Adam J. Shuhendler, Jianghong Rao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

205 Citations (Scopus)

Abstract

Semiconducting polymer nanoparticles are used as a free-radical inert and light-harvesting nanoplatform for in vivo molecular imaging of reactive oxygen and nitrogen species (RONS). This nanoprobe permits detection of RONS in the microenvironment of spontaneous bacterial infection (see picture; FRET=fluorescence resonance energy transfer).

Original languageEnglish
Pages (from-to)10325-10329
Number of pages5
JournalAngewandte Chemie - International Edition
Volume52
Issue number39
DOIs
Publication statusPublished - Sept 23 2013
Externally publishedYes

ASJC Scopus Subject Areas

  • Catalysis
  • General Chemistry

Keywords

  • biosensors
  • imaging agents
  • nanoparticles
  • polymers
  • reactive oxygen and nitrogen species

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