Site-selective C(sp3)-H amination of thioamide with anthranils under Cp∗CoIII catalysis

Rui Hua Liu; Qi Chao Shan; Xu Hong Hu; Teck Peng Loh

doi:10.1039/c9cc01715a

Site-selective C(sp³)-H amination of thioamide with anthranils under Cp∗Co^III catalysis

Rui Hua Liu, Qi Chao Shan, Xu Hong Hu^*, Teck Peng Loh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Synthetically versatile anthranils as a bifunctional amino source have been employed for the first time to enable direct amination on unactivated C(sp³)-H bonds of thioamides under Cp∗Co^III catalysis. The excellent site-selectivity on primary C(sp³)-H bonds is observed for a diverse array of thioamides with high functional group tolerance. Further applicability of the products is also highlighted through a series of interesting synthetic elaborations.

Original language	English
Pages (from-to)	5519-5522
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	38
DOIs	https://doi.org/10.1039/c9cc01715a
Publication status	Published - 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2019.

ASJC Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c9cc01715a

Cite this

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