Abstract
This work aims to find an efficient sintering technique and optimal sintering conditions of a novel sol-gel derived Bioglass®-ceramic powder so as to achieve much improved mechanical properties compared to conventional Bioglass®. To this end, the spark plasma sintering (SPS) technique was for the first time used to densify the sol-gel derived Bioglass®-ceramic powder. It was found that the sol-gel derived Bioglass®-ceramics sintered with the SPS technique at 950 °C for 15 min had a high Young's modulus value of ∼110 GPa, which was comparable to that of compact bone and significantly higher than the maximal value achieved by the conventional heat treatment. Moreover, the Bioglass®-ceramic compacts sintered with SPS released alkaline ions slowly and as a result, these highly densified Bioglass®-ceramics exhibited better cytocompatibility at the early stage of cell culture testing, compared to the conventional Bioglass®. Hence, the SPS technique is recommended to be used in the process of sol-gel derived Bioglass®-ceramics and its tissue engineering scaffolds.
| Original language | English |
|---|---|
| Pages (from-to) | 494-502 |
| Number of pages | 9 |
| Journal | Materials Science and Engineering C |
| Volume | 32 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Apr 1 2012 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Bioengineering
- Biomaterials
Keywords
- Bioglass®
- Mechanical properties
- Osteoblast
- Sol-gel
- Spark plasma sintering