State of diagnosing infectious pathogens using colloidal nanomaterials

Jisung Kim, Mohamed A.Abdou Mohamed, Kyryl Zagorovsky, Warren C.W. Chan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

36 Citations (Scopus)

Abstract

Infectious diseases are a major global threat that accounts for one of the leading causes of global mortality and morbidity. Prompt diagnosis is a crucial first step in the management of infectious threats, which aims to quarantine infected patients to avoid contacts with healthy individuals and deliver effective treatments prior to further spread of diseases. This review article discusses current advances of diagnostic systems using colloidal nanomaterials (e.g., gold nanoparticles, quantum dots, magnetic nanoparticles) for identifying and differentiating infectious pathogens. The challenges involved in the clinical translation of these emerging nanotechnology based diagnostic devices will also be discussed.

Original languageEnglish
Pages (from-to)97-114
Number of pages18
JournalBiomaterials
Volume146
DOIs
Publication statusPublished - Nov 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Ltd

ASJC Scopus Subject Areas

  • Biophysics
  • Bioengineering
  • Ceramics and Composites
  • Biomaterials
  • Mechanics of Materials

Keywords

  • Clinical translation
  • Diagnostics
  • Nanomaterials
  • Nanotechnology
  • Point of care

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