Stereoelectronic versus steric tuning in the prins cyclization reaction: Synthesis of 2fi-trans pyranyl motifs

Xu Hong Hu, Feng Liu, Teck Peng Loh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

The use of carboalkoxyl allenic alcohol for the efficient synthesis of pyranyl motifs via Prlns cycllzatlon Is described. This method provides easy access to 2,6-trans dlhydropyrans In good yield and high dlastereoselectlvlty.

Original languageEnglish
Pages (from-to)1741-1743
Number of pages3
JournalOrganic Letters
Volume11
Issue number8
DOIs
Publication statusPublished - Apr 16 2009
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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