Synthesis of a Tetrahydrofuranyl β-Amino Acid for Peptide Nucleic Acid Construction

Roderick W. Bates; Tirayut Vilaivan; Suryavanshi Padmakar Apparao; Tu Thanh Ho

doi:10.1055/s-0035-1560649

Synthesis of a Tetrahydrofuranyl β-Amino Acid for Peptide Nucleic Acid Construction

Roderick W. Bates^*, Tirayut Vilaivan, Suryavanshi Padmakar Apparao, Tu Thanh Ho

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

A tetrahydrofuranyl β-amino acid has been prepared by using the asymmetric dihydroxylation of a furyl alkene to establish the stereochemistry. The furan moiety was employed as a carboxylic acid surrogate.

Original language	English
Article number	st-2015-d0655-l
Pages (from-to)	93-95
Number of pages	3
Journal	Synlett
Volume	27
Issue number	1
DOIs	https://doi.org/10.1055/s-0035-1560649
Publication status	Published - Jan 4 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© Georg Thieme Verlag Stuttgart New York Synlett 2016.

ASJC Scopus Subject Areas

Organic Chemistry

Keywords

amino acid
dihydroxylation
furan
oxidation
tetrahydrofuran

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10.1055/s-0035-1560649

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AU - Apparao, Suryavanshi Padmakar

AU - Ho, Tu Thanh

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PY - 2016/1/4

Y1 - 2016/1/4

N2 - A tetrahydrofuranyl β-amino acid has been prepared by using the asymmetric dihydroxylation of a furyl alkene to establish the stereochemistry. The furan moiety was employed as a carboxylic acid surrogate.

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KW - furan

KW - oxidation

KW - tetrahydrofuran

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Synthesis of a Tetrahydrofuranyl β-Amino Acid for Peptide Nucleic Acid Construction

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

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