Abstract
Highly efficient asymmetric conjugate addition of MeMgBr to α,β-unsaturated esters catalyzed by CuI/Tol-BINAP, Paterson aldol, organocatalytic aldol, and cross-metathesis reactions were applied in the synthesis of C13-C23 fragment of Iriomoteolide-1a.
| Original language | English |
|---|---|
| Article number | C13509SS |
| Pages (from-to) | 3557-3564 |
| Number of pages | 8 |
| Journal | Synthesis |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 2009 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Catalysis
- Organic Chemistry
Keywords
- Asymmetric conjugate addition
- Cross-metathesis
- Iriomoteolide-1a
- Organocatalytic aldol