Synthesis of dihydrogambirtannine by alkyne [2 + 2 + 2]-cyclotrimerisation

Pattarakiat Seankongsuk; Patcharaporn Sae-Lao; Shi He; Veronica Pereira; Roderick W. Bates

doi:10.1039/d5ob00162e

Synthesis of dihydrogambirtannine by alkyne [2 + 2 + 2]-cyclotrimerisation

Pattarakiat Seankongsuk, Patcharaporn Sae-Lao, Shi He, Veronica Pereira, Roderick W. Bates^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

Abstract

The first asymmetric synthesis of (−)-dihydrogambirtannine has been achieved using nucleophilic addition to a chiral sulfinyl imine to establish the stereogenic centre and [2 + 2 + 2] alkyne cyclotrimerisation to construct the aromatic E ring.

Original language	English
Pages (from-to)	3131-3136
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	23
Issue number	13
DOIs	https://doi.org/10.1039/d5ob00162e
Publication status	Published - Feb 21 2025
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2025 The Royal Society of Chemistry.

ASJC Scopus Subject Areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/d5ob00162e

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abstract = "The first asymmetric synthesis of (−)-dihydrogambirtannine has been achieved using nucleophilic addition to a chiral sulfinyl imine to establish the stereogenic centre and [2 + 2 + 2] alkyne cyclotrimerisation to construct the aromatic E ring.",

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AU - He, Shi

AU - Pereira, Veronica

AU - Bates, Roderick W.

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Synthesis of dihydrogambirtannine by alkyne [2 + 2 + 2]-cyclotrimerisation

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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