Synthesis of phenolic natural products using palladium catalyzed coupling reactions

Roderick W. Bates; Christine J. Gabel; Jianhua Ji; Thota Rama-Devi

doi:10.1016/0040-4020(95)00441-A

Synthesis of phenolic natural products using palladium catalyzed coupling reactions

Roderick W. Bates^*, Christine J. Gabel, Jianhua Ji, Thota Rama-Devi

^*Corresponding author for this work

University of North Texas

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.

Original language	English
Pages (from-to)	8199-8212
Number of pages	14
Journal	Tetrahedron
Volume	51
Issue number	30
DOIs	https://doi.org/10.1016/0040-4020(95)00441-A
Publication status	Published - Jul 24 1995
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4020(95)00441-A

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title = "Synthesis of phenolic natural products using palladium catalyzed coupling reactions",

abstract = "Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.",

author = "Bates, {Roderick W.} and Gabel, {Christine J.} and Jianhua Ji and Thota Rama-Devi",

year = "1995",

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T1 - Synthesis of phenolic natural products using palladium catalyzed coupling reactions

AU - Bates, Roderick W.

AU - Gabel, Christine J.

AU - Ji, Jianhua

AU - Rama-Devi, Thota

PY - 1995/7/24

Y1 - 1995/7/24

N2 - Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.

AB - Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.

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U2 - 10.1016/0040-4020(95)00441-A

DO - 10.1016/0040-4020(95)00441-A

M3 - Article

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JO - Tetrahedron

JF - Tetrahedron

IS - 30

ER -

Synthesis of phenolic natural products using palladium catalyzed coupling reactions

Abstract

ASJC Scopus Subject Areas

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