Synthesis of primary amines by the electrophilic amination of Grignard reagents with 1,3-dioxolan-2-one O-sulfonyloxime

Mitsuru Kitamura, Takahiro Suga, Shunsuke Chiba, Koichi Narasaka*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

(Chemical equation presented) Primary amines are prepared by the electrophilic amination of Grignard reagents with 4,4,5,5-tetramethyl-1,3- dioxolan-2-one O-phenylsulfonyloxime and the acidic hydrolysis of the resulting imines.

Original languageEnglish
Pages (from-to)4619-4621
Number of pages3
JournalOrganic Letters
Volume6
Issue number24
DOIs
Publication statusPublished - Nov 25 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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