The AAA+ superfamily of functionally diverse proteins

Jamie Snider, Guillaume Thibault, Walid A. Houry*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

220 Citations (Scopus)

Abstract

The AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes, attaining this functional diversity through additions of structural motifs and modifications to the core AAA+ module.

Original languageEnglish
Article number216
JournalGenome Biology
Volume9
Issue number4
DOIs
Publication statusPublished - Apr 30 2008
Externally publishedYes

ASJC Scopus Subject Areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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