The emerging role of Nrf2 in dermatotoxicology

Nguan S. Tan, Walter Wahli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison-induced chloracne and metabolizing acquired dioxin-induced skin hamartomas or MADISH. A new study in this issue of EMBO Molecular Medicine reveals unsuspected biological functions of prolonged Nrf2 activation on skin homeostasis and provides novel molecular insights into MADISH.

Original languageEnglish
Pages (from-to)431-433
Number of pages3
JournalEMBO Molecular Medicine
Volume6
Issue number4
DOIs
Publication statusPublished - Apr 2014
Externally publishedYes

ASJC Scopus Subject Areas

  • Molecular Medicine

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