The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells

Hoi Yeung Li; Yixian Zheng

doi:10.4161/cc.3.8.1059

The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells

Hoi Yeung Li, Yixian Zheng^*

^*Corresponding author for this work

Howard Hughes Medical Institute

Research output: Contribution to journal › Review article › peer-review

9 Citations (Scopus)

Abstract

The RanGTPase system has multiple functions in both interphase and mitosis. Extensive studies of Ran-driven nucleocytoplasmic transport have contributed significantly toward our understanding of how RanGTP is produced, hydrolyzed, and localized in interphase. However, there is still a lack of understanding about how this system operates in mitosis. Recent advances have begun to shed light on how RanGTP is produced and localized in mitotic mammalian cells.

Original language	English
Pages (from-to)	991-993
Number of pages	3
Journal	Cell Cycle
Volume	3
Issue number	8
DOIs	https://doi.org/10.4161/cc.3.8.1059
Publication status	Published - Aug 2004
Externally published	Yes

ASJC Scopus Subject Areas

Molecular Biology
Developmental Biology
Cell Biology

Keywords

Cell cycle
Mitosis
Mitotic spindle
Ran
RanBP1
RanGAP1
RCC1

Access to Document

10.4161/cc.3.8.1059

Cite this

@article{73762a4f524348a591e1908d26d5a9be,

title = "The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells",

abstract = "The RanGTPase system has multiple functions in both interphase and mitosis. Extensive studies of Ran-driven nucleocytoplasmic transport have contributed significantly toward our understanding of how RanGTP is produced, hydrolyzed, and localized in interphase. However, there is still a lack of understanding about how this system operates in mitosis. Recent advances have begun to shed light on how RanGTP is produced and localized in mitotic mammalian cells.",

keywords = "Cell cycle, Mitosis, Mitotic spindle, Ran, RanBP1, RanGAP1, RCC1",

author = "Li, \{Hoi Yeung\} and Yixian Zheng",

year = "2004",

month = aug,

doi = "10.4161/cc.3.8.1059",

language = "English",

volume = "3",

pages = "991--993",

journal = "Cell Cycle",

issn = "1538-4101",

publisher = "Landes Bioscience",

number = "8",

}

TY - JOUR

T1 - The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells

AU - Li, Hoi Yeung

AU - Zheng, Yixian

PY - 2004/8

Y1 - 2004/8

N2 - The RanGTPase system has multiple functions in both interphase and mitosis. Extensive studies of Ran-driven nucleocytoplasmic transport have contributed significantly toward our understanding of how RanGTP is produced, hydrolyzed, and localized in interphase. However, there is still a lack of understanding about how this system operates in mitosis. Recent advances have begun to shed light on how RanGTP is produced and localized in mitotic mammalian cells.

AB - The RanGTPase system has multiple functions in both interphase and mitosis. Extensive studies of Ran-driven nucleocytoplasmic transport have contributed significantly toward our understanding of how RanGTP is produced, hydrolyzed, and localized in interphase. However, there is still a lack of understanding about how this system operates in mitosis. Recent advances have begun to shed light on how RanGTP is produced and localized in mitotic mammalian cells.

KW - Cell cycle

KW - Mitosis

KW - Mitotic spindle

KW - Ran

KW - RanBP1

KW - RanGAP1

KW - RCC1

UR - http://www.scopus.com/inward/record.url?scp=13944279881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13944279881&partnerID=8YFLogxK

U2 - 10.4161/cc.3.8.1059

DO - 10.4161/cc.3.8.1059

M3 - Review article

C2 - 15254395

AN - SCOPUS:13944279881

SN - 1538-4101

VL - 3

SP - 991

EP - 993

JO - Cell Cycle

JF - Cell Cycle

IS - 8

ER -

The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells

Abstract

ASJC Scopus Subject Areas

Keywords

Access to Document

Other files and links

Fingerprint

Cite this