The Py235 proteins: Glimpses into the versatility of a malaria multigene family

Anne Charlotte Grüner, Georges Snounou, Katy Fuller, William Jarra, Laurent Rénia, Peter R. Preiser

Research output: Contribution to journalShort surveypeer-review

25 Citations (Scopus)

Abstract

Py235 rhoptry proteins, encoded by a multigene family of the rodent malaria parasite Plasmodium yoelii, combine a functional role in invasion with one of immune evasion, and have homologues in malaria parasites of humans. Investigations of Py235 are summarised and the perspectives for dissecting the molecular and biological mechanisms underlying these crucial phenomena are discussed.

Original languageEnglish
Pages (from-to)864-873
Number of pages10
JournalMicrobes and Infection
Volume6
Issue number9
DOIs
Publication statusPublished - Jul 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Microbiology
  • Immunology
  • Infectious Diseases

Keywords

  • Invasion
  • Malaria
  • Multigene family
  • Plasmodium
  • Transcription

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