The Rotterdam Study: 2012 objectives and design update

Albert Hofman*, Cornelia M. Van Duijn, Oscar H. Franco, M. Arfan Ikram, Harry L.A. Janssen, Caroline C.W. Klaver, Ernst J. Kuipers, Tamar E.C. Nijsten, Bruno H.Ch Stricker, Henning Tiemeier, André G. Uitterlinden, Meike W. Vernooij, Jacqueline C.M. Witteman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

277 Citations (Scopus)

Abstract

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, oncological, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over a 1,000 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

Original languageEnglish
Pages (from-to)657-686
Number of pages30
JournalEuropean Journal of Epidemiology
Volume26
Issue number8
DOIs
Publication statusPublished - Aug 2011
Externally publishedYes

ASJC Scopus Subject Areas

  • Epidemiology

Keywords

  • Biomarkers
  • Cardiovascular diseases
  • Cohort study
  • Dermatological diseases
  • Endocrine diseases
  • Epidemiologic methods
  • Genetic epidemiology
  • Liver diseases
  • Neurological diseases
  • Oncology
  • Ophthalmic diseases
  • Pharmacoepidemiology
  • Psychiatric diseases
  • Renal diseases
  • Respiratory diseases

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