The synthesis of Plicatin B via the Heck reaction

Roderick W. Bates; Christine J. Gabel

doi:10.1016/S0040-4039(00)73632-X

The synthesis of Plicatin B via the Heck reaction

Roderick W. Bates^*, Christine J. Gabel

^*Corresponding author for this work

University of North Texas

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The anti-microbial natural product Plicatin B has been synthesized in 53% overall yield using a Heck reaction as the key step. The optimum conditions for this reaction have been determined. Halophenols proved much less reactive than their corresponding acetates.

Original language	English
Pages (from-to)	3547-3550
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	22
DOIs	https://doi.org/10.1016/S0040-4039(00)73632-X
Publication status	Published - May 28 1993
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "The synthesis of Plicatin B via the Heck reaction",

abstract = "The anti-microbial natural product Plicatin B has been synthesized in 53% overall yield using a Heck reaction as the key step. The optimum conditions for this reaction have been determined. Halophenols proved much less reactive than their corresponding acetates.",

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The synthesis of Plicatin B via the Heck reaction

Abstract

ASJC Scopus Subject Areas

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