Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

Teck Peng Loh; Sarah B.K.W. Liung; Kee Leng Tan; Lin Li Wei

doi:10.1016/S0040-4020(00)00221-0

Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

Teck Peng Loh^*, Sarah B.K.W. Liung, Kee Leng Tan, Lin Li Wei

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

167 Citations (Scopus)

Abstract

The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323). (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	3227-3237
Number of pages	11
Journal	Tetrahedron
Volume	56
Issue number	20
DOIs	https://doi.org/10.1016/S0040-4020(00)00221-0
Publication status	Published - May 12 2000
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

β-aminoketones
Indium trichloride
One-pot Mannich reaction

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10.1016/S0040-4020(00)00221-0

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abstract = "The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323). (C) 2000 Elsevier Science Ltd.",

keywords = "β-aminoketones, Indium trichloride, One-pot Mannich reaction",

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T1 - Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

AU - Loh, Teck Peng

AU - Liung, Sarah B.K.W.

AU - Tan, Kee Leng

AU - Wei, Lin Li

PY - 2000/5/12

Y1 - 2000/5/12

N2 - The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323). (C) 2000 Elsevier Science Ltd.

AB - The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323). (C) 2000 Elsevier Science Ltd.

KW - β-aminoketones

KW - Indium trichloride

KW - One-pot Mannich reaction

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JO - Tetrahedron

JF - Tetrahedron

IS - 20

ER -

Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

Abstract

ASJC Scopus Subject Areas

Keywords

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