Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells

Shengyan Yin; Yun Long Wu; Benhui Hu; Yu Wang; Pingqiang Cai; Chek Kun Tan; Dianpeng Qi; Liyan Zheng; Wan Ru Leow; Nguan Soon Tan; Shutao Wang; Xiaodong Chen

doi:10.1002/admi.201300043

Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells

Shengyan Yin, Yun Long Wu, Benhui Hu, Yu Wang, Pingqiang Cai, Chek Kun Tan, Dianpeng Qi, Liyan Zheng, Wan Ru Leow, Nguan Soon Tan, Shutao Wang, Xiaodong Chen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

84 Citations (Scopus)

Abstract

A hierarchical nanostructured 3D platform is reported that combines microporosity with a nanostructure for selective capture of cancer cells. The microporosity allows red blood cells to travel through, while the anti-EpCAM modified nanostructure captures circulating tumor cells. These systems allow for considerable increase in the contact frequency between target cells and the substrate, thus enhancing the cancer cell filtration and isolation efficiency.

Original language	English
Article number	1300043
Journal	Advanced Materials Interfaces
Volume	1
Issue number	1
DOIs	https://doi.org/10.1002/admi.201300043
Publication status	Published - Feb 1 2014
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

ASJC Scopus Subject Areas

Mechanics of Materials
Mechanical Engineering

Keywords

circ admi201300043 ulating tumor cells
composite
graphene
macroscopic structure

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/admi.201300043

Cite this

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title = "Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells",

abstract = "A hierarchical nanostructured 3D platform is reported that combines microporosity with a nanostructure for selective capture of cancer cells. The microporosity allows red blood cells to travel through, while the anti-EpCAM modified nanostructure captures circulating tumor cells. These systems allow for considerable increase in the contact frequency between target cells and the substrate, thus enhancing the cancer cell filtration and isolation efficiency.",

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T1 - Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells

AU - Yin, Shengyan

AU - Wu, Yun Long

AU - Hu, Benhui

AU - Wang, Yu

AU - Cai, Pingqiang

AU - Tan, Chek Kun

AU - Qi, Dianpeng

AU - Zheng, Liyan

AU - Leow, Wan Ru

AU - Tan, Nguan Soon

AU - Wang, Shutao

AU - Chen, Xiaodong

PY - 2014/2/1

Y1 - 2014/2/1

N2 - A hierarchical nanostructured 3D platform is reported that combines microporosity with a nanostructure for selective capture of cancer cells. The microporosity allows red blood cells to travel through, while the anti-EpCAM modified nanostructure captures circulating tumor cells. These systems allow for considerable increase in the contact frequency between target cells and the substrate, thus enhancing the cancer cell filtration and isolation efficiency.

AB - A hierarchical nanostructured 3D platform is reported that combines microporosity with a nanostructure for selective capture of cancer cells. The microporosity allows red blood cells to travel through, while the anti-EpCAM modified nanostructure captures circulating tumor cells. These systems allow for considerable increase in the contact frequency between target cells and the substrate, thus enhancing the cancer cell filtration and isolation efficiency.

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KW - graphene

KW - macroscopic structure

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Three-Dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

UN SDGs

Access to Document

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